Functional Medicine Course for Infectious Disease: LH COVID, EBV & Lyme Disease
Become the provider these patients have been searching for – and build a cash-pay functional medicine practice around the three most underserved chronic-illness populations in medicine.
Long COVID, chronic Epstein-Barr, and chronic Lyme overlap, mimic each other, and share the same root drivers – persistent infection, immune dysregulation, and runaway inflammation. Most of these patients have been dismissed, misdiagnosed, and bounced from office to office while their labs come back "normal." Almost no one will treat them. This course gives you the pathophysiology, the workup, and the full functional medicine toolkit to become the provider who finally does – across all three conditions – and to build a recurring, cash-pay practice around them.
A large, desperate, cash-pay market that conventional medicine is turning away.
These are complex, recurring, cash-pay conditions by nature. The instructor already earns $70,000 a year in passive supplement-dispensary income alone from this patient base, and this course shows you how to set that up. Add complex-case management, advanced labs, and IV therapy, and you have a durable, high-retention practice.
5 CE Hrs - 2.5 Rx Hrs - $499
Three overlapping epidemics, almost no supply
The demand is enormous and the conditions run together. There have been roughly 112 million reported COVID cases in the US, and 8.4 percent of adults said they had experienced long COVID as of 2023. Layered on top are chronic Epstein-Barr reactivation – associated with poorer long-term outcomes – and chronic Lyme, where roughly 70 percent of patients resolve with the right antibiotic strategy and two-thirds respond to a treatment trial. These conditions overlap constantly: a single patient may carry all three, and co-infection routinely drives brain inflammation and neuro-psychiatric symptoms that get misread as a mental health disorder. Conventional medicine sends these patients away as "normal." That mismatch between overwhelming demand and almost no supply is the opening this course teaches you to fill – and complex, cash-pay patients who finally find help do not leave, and they do not stop referring.
Why this is a durable, recurring revenue line
Complex chronic infection is a managed relationship, not a single visit – and the clinical model builds the recurring cadence for you. Inflammatory markers are rechecked every 3 to 5 months, thyroid labs every 8 to 10 weeks during titration, iron every 4 months. Low-dose naltrexone is uptitrated over 90 to 120 days. Antibiotic courses for Lyme run weeks to months. IV immunoglobulin runs daily for 4 to 5 days, then monthly for 6 months. Patients follow up every 4 to 6 months with repeat labs and symptom questionnaires. Every one of those touchpoints is a scheduled, cash-pay visit.
Revenue multipliers built into the model
One infectious-disease workup rarely stays one service. The same patient needs a supplement protocol (a dispensary the instructor runs at $70,000 a year in passive income), advanced labs (Lyme panels, MCAS panels, GI-MAP, thyroid, spike-protein and EBV testing), thyroid optimization, and often IV therapy – IV immunoglobulin and IV glutathione the course teaches. And because these patients have spent years being disbelieved, the one who recovers becomes a vocal, loyal referral source in a community that talks.
A framework you monetize, condition by condition
The course moves from mechanism to management across all three diseases: how persistent infection and immune dysregulation drive chronic illness, and how to treat the results with a functional medicine approach. Each piece is both a clinical competency and a reason a patient keeps coming back:
Shared pathophysiology – your diagnostic authority. Persistent spike protein and IL-6-driven inflammation in long COVID, EBV reactivation and cytokine dysregulation, and Lyme's intracellular and extracellular persistence. The mechanistic fluency that explains what no one has explained to the patient.
The 10 affected organ systems & the Classic 5 Impacts – your comprehensive intake. Brain inflammation, mitochondrial crashing, microclots, viral reactivation, and illness amplifiers show up across all three conditions. A whole-body assessment opens multiple service lines per patient.
Telling the three apart – and spotting co-infection – your differentiator. Long COVID, EBV, and Lyme overlap with each other and with MCAS, ME/CFS, and fibromyalgia. Recognizing which are in play is what captures the misdiagnosed and expands your treatable population.
The treatment toolkit – your recurring service menu. Staged protocols spanning combination antibiotics for Lyme, antivirals for EBV, IV Ig, low-dose naltrexone, thyroid optimization, the FLCCC approach, and targeted supplements – each a titrated, monitored, recurring engagement.
The supplement dispensary – your passive-income line. How to set up a dispensary, set your own rates, and earn on protocols you are already recommending. The instructor runs this at $70,000 a year.
What you will be able to do, and build a practice around
By the end of this course you will be able to:
Explain the pathophysiology of long COVID, EBV reactivation, and chronic Lyme, including persistent infection and IL-6-driven inflammation. Mechanistic authority is what converts a skeptical, previously-dismissed patient into a committed one.
Identify the organ systems and the Classic 5 Impacts, distinguish the three conditions, and recognize overlap with MCAS, ME/CFS, and fibromyalgia. A wider diagnostic net is a larger treatable, cash-pay population.
Order and interpret the relevant labs – inflammatory, metabolic, thyroid, Lyme, EBV, MCAS, and spike-protein markers. The recheck cadence these labs require is a built-in, repeatable visit schedule.
Build staged, individualized management plans across all three diseases – antibiotics, antivirals, IV Ig, LDN, thyroid, supplements – and titrate them safely. Each titration and follow-up is a recurring, billable engagement.
Set up a supplement dispensary and ancillary cash-pay services (advanced labs, IV therapy) – turning your clinical recommendations into a passive-income line the instructor runs at $70,000 a year.
The clinical engine, framed as your practice
Your Diagnostic Authority: Shared Pathophysiology
How SARS-CoV-2 spike protein persists and drives neuroinflammation, how EBV reactivates and perpetuates cytokine dysregulation, and how Borrelia persists in intracellular and extracellular compartments. This is the explanation the patient has never received – and the credibility that starts a long-term relationship.
Your Comprehensive Intake: 10 Systems & the Classic 5
The full symptom picture across ten disease categories, plus the Classic 5 Impacts – brain inflammation, mitochondrial crashing, cardiovascular and metabolic comorbidities with microclots, viral reactivation, and illness amplifiers – which recur across all three conditions. A whole-body workup surfaces multiple treatable problems – and multiple service lines – in a single patient.
Your Differentiator: Telling the Three Apart
Long COVID vs. EBV reactivation vs. chronic Lyme – how to distinguish them, evaluate them (including time-sensitive MCAS panels and Lyme testing), and recognize the co-infections that drive brain inflammation and neuro-psychiatric symptoms. Every condition you can identify is a patient other clinics send away and you can treat.
Your Recurring Service Menu: The Treatment Toolkit
Staged, individualized protocols: combination antibiotics for Lyme (covering intracellular and extracellular organisms), antivirals for EBV, IV immunoglobulin, low-dose naltrexone uptitration, thyroid optimization with liothyronine, the FLCCC approach, and targeted supplement and nutrition plans. Each is titrated and monitored over months – recurring, cash-pay engagements, not one-off visits.
Your Passive-Income Line: The Dispensary
How to set up a supplement dispensary that interfaces with your EMR, set your own discount and rates, and earn on the protocols you already recommend. The instructor runs this at $70,000 a year in side income – a model you can replicate from your first patient.
Your Proof: A Real Case, Tracked
A 42-year-old patient with overlapping infection and inflammation walked from a spike protein over 20,000, hs-CRP of 376, and hypothyroid, insulin-resistant labs to measurable improvement at four months (spike 18,000, CRP 257, rising iron and free T3), continuing follow-up every 4 to 6 months. The documented turnaround that sells the next patient and earns the referral.
The modules
Course Expiration: 09/30/2029
Foundations & Epidemiology.
Definitions of long COVID, EBV reactivation, and chronic Lyme, the conditions they mimic (ME/CFS, fibromyalgia, autoimmune), the statistics, and the risk factors – establishing just how large and underserved this cash-pay population is.
Shared Pathophysiology.
Persistent infection and immune dysregulation across all three diseases – spike protein and IL-6, EBV reactivation, and Borrelia persistence – the mechanistic authority that anchors patient trust.
Organ-System Impact & the Classic 5.
The ten affected disease categories and the five core drivers, including the neuro-psychiatric burden that co-infection intensifies – a whole-body map that opens multiple service lines.
Differentiation, Overlap & Co-Infection.
Distinguishing long COVID, EBV, and Lyme; MCAS/MIS recognition and time-sensitive evaluation; and Lyme testing – why capturing these conditions expands your treatable base.
Workup & Lab Interpretation.
Inflammatory, metabolic, thyroid, Lyme, EBV, MCAS, and spike-protein testing, read against optimal targets – with the recheck cadence that creates recurring visits.
Management & Protocols.
Staged treatment across combination antibiotics for Lyme, antivirals for EBV, IV Ig, LDN, thyroid optimization, the FLCCC approach, sleep and microbiome support, and lifestyle – the recurring, titrated core of the practice.
Building the Practice.
Setting up the supplement dispensary (the instructor's $70,000-a-year passive-income line) and layering advanced labs and IV therapy as ancillary cash-pay services.
Who should enroll
The NP who wants to open a cash-pay functional medicine practice. This is the clinical framework and the business model to build one around long COVID, EBV, and Lyme – markets desperate for providers and built for recurring, insurance-free care.
The NP adding a high-retention service line to an existing practice. Chronic-infection management, thyroid optimization, and a supplement dispensary bolt onto a primary care, functional, or wellness practice and turn one-time patients into months-long, referring relationships.
The NP tired of telling sick patients their "normal" labs mean nothing can be done. If you want to actually resolve the fatigue, brain fog, and inflammation these patients live with, this is the framework that lets you – and a differentiated market position.
The NP who wants to serve the dismissed and be the provider they refer everyone to. A disbelieved, underserved patient base is both deeply rewarding to treat and a durable, referral-rich foundation for a practice.
Frequently asked questions
How do I actually make money treating these conditions?
It is a cash-pay, recurring model. A patient starts with a comprehensive workup, returns for lab rechecks and protocol titration every 8 to 10 weeks during active treatment, and follows up every 4 to 6 months after – with a supplement dispensary (the instructor's line runs at $70,000 a year), advanced labs, and IV therapy layered on top. One patient is a months-long, multi-service relationship.
What is the fastest path to a first revenue line?
Start with the workup and a supplement dispensary. The workup requires no equipment and immediately creates the recheck cadence that drives recurring visits, and the dispensary earns passive income on protocols you are already recommending. IV therapy and advanced labs layer on as you grow.
Do I need to treat all three diseases to use this?
No – but they overlap so often that treating them together is the point. Many patients carry more than one, and co-infection is a major driver of the neuro-psychiatric symptoms other clinics miss. The course teaches you to recognize and manage each condition and the overlap between them, which is exactly what widens your treatable population.
How do I get patients to refer other patients?
Deliver what no one else has for them – a real diagnosis and measurable improvement. This is a population that has been disbelieved for years; the patient who recovers becomes a vocal, loyal referral source in a community that shares provider names constantly.
Are these treatments within my scope, and are they proven?
The protocols are built for nurse practitioners, and the course spans conventional and integrative, sometimes off-guideline options (for example, the FLCCC and nicotine protocols). They are presented as clinical options to weigh against risks and benefits, not guaranteed cures. Confirm your state scope, use clinical judgment, and set realistic patient expectations.
Do I need to take insurance?
No. Complex chronic-infection care is a cash-pay model by design – it frees you to treat to optimal targets and off-guideline options rather than reimbursement rules, and it is what makes the recurring-relationship and dispensary economics work.